Search results for "pharmacology [Erythropoietin]"
showing 10 items of 257 documents
�ber den Zusammenhang zwischen positiv inotroper Wirkung von Digitoxigenin, Kaliumflux und intracellul�ren Ionenkonzentrationen im Herzmuskel
1962
Der wirkungsmechanismus der Herzglykoside wird von einer Reihe von Untersuchern uber eine Hemmung des aktiven Ionentransportes, bzw. eine Veranderung der intracellularen Kalium- und Natriumkonzentration, erklart. Hierdurch wurden Bedingungen geschaffen, die einen positiv inotropen Effekt zur Folge hatten.
Involvement of phospholipid metabolism in the events of the oxidative burst of granulocytes
1984
In summary we provide now evidence for specific interactions between the phospholipid metabolism and the oxidative burst. Lysophosphatidylcholine-like molecules showed specific enhancement of the oxidative burst and the capacity to replace phospholipase A2 function. Our findings might be useful in further studying the events occurring on the way from receptor stimulation to activation of the oxidative burst.
�ber die Wirkung von Strophanthidin-3-bromacetat am Papillarmuskel des Meerschweinchens
1971
In experiments on isolated, electrically stimulated papillary muscles or auricles of guinea pig hearts some characteristics of the inotropic action of strophanthidin-3-bromaocetate (SBA), a derivative of k-strophanthidin which is supposed to be an irreversible inhibitor of the (Na+-K+)-activated ATPase, were studied and compared with the behaviour of k-strophanthidin and digitoxin.
Influence of intracellular sodium concentration on calcium influx in isolated guinea pig auricles.
1969
Levetiracetam in the treatment of vascular chorea: a case report
2004
Die Wirkung von Thiopental-Natrium und Pentobarbital-Natrium auf die Nierengef��e von M�usen
1957
The action of intravenous injections of pentobarbital and of thiopental on the blood pressure and on the vascular tone in the cortex of the kidney has been studied in albino mice. Pentobarbital caused a pronounced decrease of the filling of blood vessels in the cortex of kidneys together with a long-lasting anaesthesia and a long lasting fall of blood pressure. Thiopental, on the other hand, was less effective on the filling of blood vessels, while its narcotic effect was small and the fall of blood pressure less pronounced. The results indicate that both substances increased the vascular tone in the cortex of the kidney.
Influence of the suspension of continued treatment with flurazepam and amobarbital on two discrimination learning schedules.
1977
The authors have studied the effect of the suspension of chronic treatment with flurazepam and amobarbital on the operant behavior of rats that for the first time were in the presence of two fixed-interval discrimination schedules. With the sound discrimination schedule, the responses emitted by the treated animals had characteristics similar to those of control animals. With the temporal discrimination schedule, though it is not possible to distinguish between learning rates, modifications in the intensity of the effect (increases in lever pressing) indicate that, considering the doses, the action of flurazepam is slight and that of amobarbital clear and statistically significant.
Effect of a "therapeutic" concentration of digitoxigenine on myocardial potassium and sodium content in Ca-poor media.
1972
The effect of 3·10−7 g/ml digitoxigenine on cellular K and Na concentrations, [K]i and [Na]i, water content, extracellular space, and contractile force was investigated in isolated electrically stimulated left guinea-pig auricles at reduced extracellular Ca concentration (0.45 mM). Digitoxigenine, which increased contractile force without producing arrhythmias or contractures, decreased [K]i and enhanced [Na]i. Water content and extracellular space remained unchanged. It is concluded that digitoxigenine can decrease myocardial [K]i and increase [Na]i even in “therapeutic” concentrations, provided that the experiments are performed in Ca-poor media.
DMPP and the adrenergic nerve terminal: mechanisms of noradrenaline release from vesicular and extravesicular compartments.
1977
DMPP (1,1-dimethyl-4-phenylpiperazine) in various concentrations between 1.6×10−6 M and 6.2×10−5 M was infused into isolated rabbit hearts to study the neuronal release and uptake of noradrenaline.